![]() Children: Niacinamide is likely safe when taken by mouth in the recommended amounts by age. The maximum recommended amount while pregnant or breast-feeding is 30 mg daily for those under 18 years of age, and 35 mg daily for those over 18 years of age. Special precautions & warnings: Pregnancy and breast-feeding: Niacinamide is likely safe when taken in recommended amounts. Niacinamide cream might cause mild burning, itching, or redness. When applied to the skin: Niacinamide is possibly safe. It might cause side effects such as stomach upset, gas, dizziness, headache, and rash. Niacinamide is possibly safe when taken in doses up to 900-1500 mg daily. ![]() ![]() Niacinamide-containing foods or supplements are safe when taken in doses lower than 35 mg daily. Prescription products containing niacinamide are safe when taken as directed. When taken by mouth: Niacinamide is likely safe when used appropriately. There is interest in using niacinamide for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful. Taking niacinamide by mouth while undergoing chemotherapy doesn't seem to benefit people with brain tumors. Taking niacinamide by mouth seems to improve joint flexibility and reduce pain and swelling in people with osteoarthritis. Taking niacinamide by mouth seems to help prevent new skin cancer or precancerous spots from forming in people with a history of nonmelanoma skin cancer. In people who need hemodialysis due to kidney failure and have high levels of phosphate, taking niacinamide by mouth seems to help decrease phosphate levels. High levels of phosphate in the blood (hyperphosphatemia).Taking niacinamide by mouth might help slow the progression of type 1 diabetes. Applying a cream containing niacinamide seems to improve the appearance of skin in people with acne. It's sometimes preferred over niacin because it doesn't cause flushing, a side effect of niacin treatment. Niacinamide prescription products are US FDA approved for preventing and treating pellagra. A disease cause by niacin deficiency (pellagra).The effectiveness ratings for NIACINAMIDE are as follows: Likely effective for. Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
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